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Population Genetics and Variation
Population Genetics and Variation
Genetic basis for Anopheles arabiensis refractoriness to Plasmodium falciparum in rice cultivating zones in central and western Kenya
Damaris Matoke
Kenya Medical Research Institue, Kenya
Anopheles arabiensis mosquitoes are amongst the most important malaria vectors in sub-tropical Africa. It’s predominant in areas of rice agriculture. Refractoriness to malaria parasites has been known to occur in Anopheles mosquitoes. This study seeks to determine basis of refractoriness and QTLs controlling refractoriness to Plasmodium falciparum in Anopheles arabiensis
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Population Genetics and Variation
Evaluation of in silico Single Nucleotide Polymorphisms Discovery in Expressed Sequence Tags
Erika Souche, Bart Hellemans, Jeroen Van Houdt, Adelino Canario, Sven Klages, Richard Reinhardt, Filip Volckaert
Laboratory of Aquatic Ecology, Belgium
Three in silico Single Nucleotide Polymorphisms (SNPs) discovery tools are tested on the same Expressed Sequence Tag (EST) dataset. Randomly chosen SNP candidates are validated by direct sequencing. Comparing algorithms and results of each tool can reveal the factors that are essential for an accurate in silico SNP discovery.
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