ISCB Student Council: Next Generation Computational Biologists

Welcome to the ISCB Student Council, the student organization of the International Society for Computational Biology.

Our mission is to promote the development of the next generation of computational biologists. We achieve our goal through provision of scientific events, networking opportunities, soft-skills training, educational resources and career advice, while attempting to influence policy processes affecting science and education. The Student Council website is a resource for the global computational biology student community and we allow you to get in touch with your peers and to find out about events and initiatives for computational biology students - no matter where in the world you are. If you have questions or comments don't hesitate to contact us.

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The tentative conference program is now available on the symposium website. The full symposium booklet including talk abstracts and information about our two wonderful keynote speakers is available on the ISMB app. Download it now for iOS and Android.

See you in Orlando!

We are pleased to announce that we have confirmed our first keynote speaker: Prof. Ruth Nussinov (Professor and Senior Principal Investigator, National Cancer Institute and Tel Aviv University). Prof. Nussinov is one of the leading scientists in the Structural Computational Biology Field.

Ruth Nussinov’s algorithm for the prediction of RNA secondary structure is still the leading method. She proposed ‘Conformational Selection and Population Shift’ as an alternative to the textbook ‘Induced-Fit’ model in molecular recognition. Her recent studies unveiled the key role of allostery under normal conditions and in disease and the principles of allosteric drug discovery. She uncovered the structural basis for cancer signaling, and its mechanistic principles; predicted GTP-dependent K-Ras dimer structures and suggested that K-Ras4B dimerizes via two distinct interfaces and explained the consequences for Raf’s activation and MAPK signaling; elucidated calmodulin’s role in KRAS-driven adenocarcinomas; the critical role of oncogenic KRAS in the initiation of cancer through deregulation of the G1 cell cycle, and proposed a new view of Ras isoforms. This new view argues for multiple signaling states of palmitoylated Ras isoforms, such as K-Ras4A. This view questions the completeness and accuracy of small GTPase Ras isoform statistics in different cancer types and calls for reevaluation of concepts and protocols. Importantly, the multiple signaling states also call for reconsideration of oncogenic Ras therapeutics.

Dr. Nussinov serves as the Editor-in-Chief of PLOS Computational Biology and she is an elected Fellow of the Biophysical Society. She is a Highly Cited Researcher (ranking among the top 3000 researchers or 1% across all fields according to Thomson Reuters Essential Science Indicators, http://highlycited.com/ (link is external) "earning them the mark of exceptional impact").

[Source: https://ccr.cancer.gov/Cancer-and-Inflammation-Program/ruth-nussinov]

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Upcoming Events


Student Council Symposium 2018
Directly preceding ISMB 2018
6 July 2018
Chicago, USA

European Student Council Symposium 2018
Directly preceding ECCB 2018
8 September 2018
Athens, Greece

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ISCB Student Council Shop

Official Shop

 

Did you always want to get your own personal Student Council coffee mug or T-shirt? You can now buy these and many other Student Council-branded items in the ISCB Student Council Shop. Even better: At the same time you will be supporting our work! More ...